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Cialis is the brand name for the drug Tadalafil. Tadalafil is a type of medication used to treat erectile dysfunction, a condition where men find it difficult to get or maintain an erection. Cialis works by increasing blood flow to the penis so you can get and keep an erection.

Tadalafil is the generic form of the brand Cialis®. Both medications work similarly in the body.

Cialis® is a type of medication known as a PDE5 inhibitor that is used to treat erectile dysfunction and benign prostatic hyperplasia. It comes in several different doses and can be taken either as-needed or daily for erectile dysfunction.

What is the difference between Viagra and Cialis?

The difference between Cialis and Viagra and other ED medications is that it tends to be longer lasting. While Viagra works for three to five hours, a typical dose of Cialis keeps working for 24 to 36 hours in your body.

What is Cialis?

Cialis® is a drug that is used to treat erectile dysfunction (ED). It comes in four doses, 2.5 mg, 5 mg, 10 mg, and 20 mg. Cialis® can be taken as needed in any of the four doses. The 2.5 mg and 5 mg doses are also approved for daily use for ED. Cialis® in the 2.5 mg and 5 mg doses is also FDA-approved for men suffering from urinary symptoms due to benign prostatic hyperplasia (BPH) with or without ED. Physicians on the Roman platform do not currently treat BPH. If you feel you need Cialis for the treatment of BPH, please seek in-person care. For as needed dosing, the 10 mg dose is the most commonly used dose, although some people may benefit from higher or lower doses. Cialis® is part of a “family” of medicines used to treat ED called phosphodiesterase-5 inhibitors (PDE5i). Other drugs in this family include Viagra (sildenafil), Levitra (vardenafil), and Stendra (avanafil). All of these drugs have the same mechanism of action, but there are subtle differences that may lead the doctor or nurse practitioner to recommend one drug over the other based on your treatment goals.

What is tadalafil?

Tadalafil is the chemical name of the active ingredient in Cialis®. Cialis® was originally patented and sold by Eli Lilly. It is FDA-approved to treat ED and urinary symptoms due to BPH. After the patent expired in 2018, the FDA gave permission to other drug companies to manufacture a generic version of Cialis®. The FDA requires generic drugs to be bioequivalent to the brand name version. This means that they act the same way in the body and are expected to produce the same effects as the original brand name drug. Generic drugs are generally much cheaper than the original brand name drug, and most drugs prescribed in the US are generic.

How does Cialis work?

In order to understand how Cialis® works to treat ED, it’s important to first understand the basics of how erections work. Erotic stimulation (by physical touch, erotic thoughts, smells, etc.) causes the local tissues to release nitric oxide (NO), which increases the amount of a chemical called cyclic guanosine monophosphate (cGMP). cGMP causes the muscles on the sides of the penis, the corpora cavernosa, to relax allowing blood to rush into the penis. At the same time veins that drain blood from the penis get compressed causing the increased blood to be trapped in the penis causing an erection. An enzyme called phosphodiesterase-5 breaks down cGMP leading the penis to return to its flaccid state. PDE5i, like Cialis®, block this enzyme leading to higher levels of cGMP and improving the ability to obtain and maintain an erection.

How should I take Cialis?

Cialis® should be taken at least 30–60 minutes before sex. Cialis is a long acting drug and will stay active in your body for up to 36 hours, which is sometimes why it’s nicknamed “the weekend pill.” Some people have better results when they take Cialis® at least 2 hours before sex. Cialis® absorption is not affected by food and can be taken with or without food.

1. Take at least 30–60 minutes before sex.

2. Some people have better results when they take Cialis® at least 2 hours before sex.

3. Cialis is a long acting drug and will stay active in your body for up to 36 hours.

4. Cialis® absorption is not affected by food and can be taken with or without food.

What is daily Cialis?

In addition to as needed dosing, Cialis® is also approved for daily use in the 2.5 mg and 5 mg doses. This creates a steady amount of medicine in the blood and completely eliminates the need to plan for sex. With daily Cialis®, treatment for ED becomes part of your daily routine. Most men who are eligible for ED treatment can take daily Cialis® with certain exceptions, including airline pilots, air traffic controllers, and people taking certain medicines (e.g., some HIV medicines, certain antibiotics and antifungals). You should speak with your doctor or nurse practitioner to determine if daily Cialis is an appropriate treatment option for you.

How to take Cialis?

Cialis tablets come in different strengths such as 10mg and 20mg. The tablets can be taken with or without food. Cialis dosing should not be repeated within 72 hours.

Cialis is also available in a smaller daily dose (2.5 or 5mg) for people that have sex frequently and prefer not to worry about dosing on-demand.

Who should not take Cialis?

Cialis isn’t for everyone. You should not take Cialis if any of the following conditions apply to you:

      • You have previously experienced an allergic reaction to Tadalafil (Cialis) or any other medicines in the past
      • You are taking medicines called nitrates for chest pain
      • You are currently taking take any guanylate cyclase stimulators, like riociguat (adempas)
      • You are using drugs such as amyl nitrate or amyl nitrite, and butyl nitrate, also known as poppers.
      • You have a serious liver or heart problem
      • You have low blood pressure or a condition that may lower blood pressure like aortic stenosis or hypertrophic obstructive cardiomyopathy
      • You have recently had a heart attack or stroke
      • You are taking other medication for erectile dysfunction, such as Viagra.

Is Cialis over the counter?

In USA, Cialis is not available over the counter, so you will always need a prescription first.

If you are experiencing the symptoms of erectile dysfunction and are seeking a prescription for Cialis, talk to a doctor about whether it could be the right solution.

What should you know before taking Cialis

Contraindications

Who should not take Cialis® or generic Cialis®?

Do not take Cialis® or generic Cialis® if you:

      • take medicines called nitrates (such as nitroglycerin)
      • use street drugs called “poppers” such as amyl nitrate or amyl nitrite, and butyl nitrate
      • take any medicines called guanylate cyclase stimulators such as riociguat (Adempas)
      • are allergic to Cialis® or any of the ingredients in Cialis®. See the end of this section for a complete list of ingredients in Cialis®.

What should I tell my healthcare provider before taking Cialis® or generic Cialis®?

To make sure Cialis® is safe for you, tell your healthcare provider if you have any of the following before you take Cialis® or generic Cialis®:

      • Have or have had heart problems such as a heart attack, irregular heartbeat, angina, chest pain, narrowing of the aortic valve, or heart failure
      • Have pulmonary hypertension
      • Have had a stroke
      • Have low blood pressure, or high blood pressure that is not controlled
      • Have a deformed penis shape
      • Have had an erection that lasted for more than 4 hours
      • Have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia
      • Have retinitis pigmentosa, a rare genetic (runs in families) eye disease
      • Have ever had severe vision loss, including an eye problem called NAION
      • Have bleeding problems
      • Have or have had stomach or intestinal ulcers
      • Have liver problems
      • Have kidney problems or are having kidney dialysis
      • Have any other medical conditions

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Cialis® and generic Cialis® may affect the way other medicines work, and other medicines may affect the way Cialis® and generic Cialis® works, causing side effects.

Drug interactions

Tell your healthcare provider if you take any of the following because these drugs interact with Cialis® and generic Cialis®:

      • Medicines called nitrates
      • Medicines called guanylate cyclase stimulators such as Adempas® (riociguat)
      • Medicines called alpha-blockers such as Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl), Uroxatral® (alfuzosin HCl), Jalyn® (dutasteride and tamsulosin HCl), or Rapaflo® (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients, the use of VIAGRA® or generic VIAGRA® with alpha-blockers can lead to a drop in blood pressure or to fainting
      • Medicines called HIV protease inhibitors, such as ritonavir (Norvir®), indinavir sulfate (Crixivan®), saquinavir (Fortovase® or Invirase®), or atazanavir sulfate (Reyataz®)
      • Oral antifungal medicines, such as ketoconazole (Nizoral®) and itraconazole (Sporanox®)
      • Antibiotics, such as clarithromycin (Biaxin®), telithromycin (Ketek®), or erythromycin
      • Other medicines that treat high blood pressure
      • Other medicines or treatments for ED
      • Adcirca® (tadalafil) is used to treat a rare disease called pulmonary arterial hypertension (PAH) and has the same active ingredient as Cialis®. Cialis® and generic Cialis® should not be used with Adcirca® or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such as Revatio® [sildenafil citrate])

Ask your healthcare provider or pharmacist for a list of these medicines, if you are not sure.

Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

Cialis® side effects

What are the possible side effects of Cialis® and generic Cialis®?

Cialis® and generic Cialis® can cause serious side effects. Rarely reported side effects include:

  • an erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis.
  • sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). It is uncertain whether PDE5 inhibitors directly cause the vision loss. Stop taking Cialis® and call your healthcare provider right away if you have sudden vision loss in one or both eyes.
  • sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you have these symptoms, stop takingCialis® or generic Cialis® and contact a doctor right away.

The most common side effects of Viagra® and generic Cialis® are:

  • headache
  • flushing
  • upset stomach
  • abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision
  • stuffy or runny nose
  • muscle pain
  • nausea
  • dizziness
  • rash

In addition, heart attack, stroke, irregular heartbeats and death have happened rarely in men taking Cialis® . Most, but not all, of these men had heart problems before taking Cialis® . It is not known if Cialis® caused these problems.

Does Cialis increase sex drive?

Cialis won’t make you hornier or help you feel sexually aroused when you otherwise wouldn’t be interested in sex. Cialis simply makes it easier to get an erection when you’re already sexually aroused.

Can you drink alcohol when taking Cialis?

According to the manufacturer, drinking excessive alcohol (they define it as 5 glasses of wine or 5 shots of whiskey) can increase your chances of getting a headache or getting dizzy, your heart rate increasing, or lowering your blood pressure.

If you’re planning on having a single beer or glass of wine you may not experience a difference in effectiveness.

However, it is still sensible to minimize alcohol consumption when taking Cialis and alcohol.

Does Cialis increase your size?

Cialis does not make you bigger. By relaxing the blood vessels around the penis, Cialis and other PDE5 inhibitors may help you get and maintain an erection, but this process will do nothing for your size.

Having more blood flowing in there might make it feel bigger. More blood flowing to the penis can give you a firmer erection that may alter the sexual experience for you and your partner.